Christian A. Vedeler

Department of Neurology,
Haukeland University Hospital
5021 Bergen
Norway
Tel : +47 5597-5044
Fax: +47 5597-5165

Dr. Vedeler is a clinical neurologist and professor of neurology with special interest in neuroimmunology. He is the chairman of the section of neurology and department of clinical medicine at the University of Bergen. He is also the leader of the neurology research laboratory.

Scientific Team
The group consists of Chr. Vedeler, MD PhD, 3 PhD students: Anette Storstein MD, Sissel Monstad MSc and Anette Knudsen MSc; and Mette Haugen who works as technician.

Research facilities
The research laboratory has modern equipment for immunological and genetic research. Immunohistochemistry and immuno-dot blot techniques are used for the routine detection of onconeural antiodies such as anti-Hu, Yo, Ri, amphiphysin, CRMP5, Ma, Tr. We also test for anti-titin and MAG using ELISA and anti-AChR and VGCC using RIA.

 

Areas of interest

• Development of antibody tests such as in vitro transcription and translation technique.
• Detection of new onconeural antibodies by cDNA library.
• Pathogenic mechanisms of onconeural antibodies.

Relevant Publications
1. Storstein A, Vedeler C. Neuropathy and malignancy: a retrospective study. J. Neurol 2001:248:322-7
2. Storstein A, Monstad SE, Nakkestad HL, Husebye ES, Vedeler CA. Paraneoplastic antibodies against HUD detected by a sensitive radiobinding assay. J. Neurol 2004, 251:197-203
3. Monstad SE, Drivsholm L, Storstein A, Aarseth JH, Haugen M, Lang B, Vincent A, Vedeler CA. Hu and voltage-gated calcium channel (VGCC) antibodies related to the prognosis of small-cell lung cancer. J Clin Oncol 2004, 22:795-800
4. Storstein A, Knudsen A, Bjørge L, Meri S, Vedeler C. Heterogenous expression of CD59 on human Purkinje cells. Neurosci Lett 2004, 362:21-25