Jan JGM Verschuuren
Department of Neurology
Leiden University Medical Center
PO Box 9600
Albinnsdreef, 2
2300 RC Leiden
Netherlands
Tel : +31 71 5265240
Fax: +31 71 5248253
Website LUMC: www.lumc.nl
Dr. J.J.G.M Verschuuren was born in 1961 in Breda,The Netherlands.1989
PhD: "Experimental autoimmune myasthenia gravis. Antibodies, idiotypes
and anti-idiotypes"
1995 Registration as Neurologist, University of Maastricht. Head: Prof.
dr. J. Troost
1994-June 1995 Research-fellowship Memorial Sloan-Kettering Cancer Center,
New York,USA. Department of Neurology. Head: Prof. Dr. J.B. Posner.
1995-now Neurologist at Leiden University Medical Center, Leiden, The
Netherlands.
Head: Prof. Dr. R.A.C. Roos
Scientific Team
Paul Wirtz, MD, PhD-student working on Lambert-Eaton myasthenic syndrome
Erik Niks, MD, PhD-student working on seronegative myasthenia gravis
Chiara Straathof, Neurologist, fellow neuromuscular diseases
Truus Plandsoen, MD, PhD, child neurologist
Collaborations in Leiden University Medical Center:
Gert van Dijk, PhD, Prof, clinical neurophysiology
Joop van Gerven, PhD, Prof, clinical pharmacology
Jaap Plomp, PhD, experimental studies on the neuromuscular synaps
Peter Molenaar, PhD, experimental studies on the neuromuscular synaps
.
Research facilities:
Neurophysiology laboratory
Neuropathology laboratory
Immunohaematology (HLA-studies, FACS analysis)
Neurology laboratory (ELISA, RIA, CSF studies)
Areas of interest:
Lambert-Eaton myasthenic syndrome and myasthenia gravis.
Selected Publications
1. Verschuuren JJ, Dalmau J, Hoard R, Posner JB. Paraneoplastic anti
Hu serum: studies on human tumor cell lines. J Neuroimmunol 1997 Nov;79:202
10
2. Verschuuren JJ, Dalmau J, Tunkel R, et al. Antibodies against the
calcium channel beta subunit in Lambert Eaton myasthenic syndrome.Neurology
1998;50:475 9
3. Verschuuren JJ, Perquin M, ten Velde G, et al. Anti Hu antibody titre
and brain metastases before and after treatment for small cell lung
cancer. J Neurol Neurosurg Psychiatry 1999;67:353 7
4. Wirtz PW, Nijnuis MG, Sotodeh M, et al. Dutch Myasthenia Study Group.
The epidemiology of myasthenia gravis, Lambert-Eaton myasthenic syndrome
and their associated tumours in the northern part of the province of
South Holland. J Neurol. 2003;250:698-701
5. Wirtz PW, Huizinga TW, Stoeken DJ, Wintzen AR, Verschuuren JJ. High
innate production of interleukin-10 and tumor necrosis factor-alpha
contributes to susceptibility for non-paraneoplastic Lambert-Eaton myasthenic
syndrome. J Neuroimmunol. 2003;140:194-197
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