1976: Graduation at the University of Messina Medical School
1978-79: Research fellow at Muscular Dystrophy Group Laboratory, University
of Newcastle upon Tyne, UK
1980: Board in Neurology, University of Messina
1985-86: Research fellow at Neuromuscular Center, University of Southern
California, Los Angeles, USA
1994: Full Professor of Neurology, University of Messina
2001-02: President of the Italian Association of Neuropathology
2000-03: President of the Italian Association of Myology
2006-2009: Chairman of the Department of Neurosciences, Psychiatry and Anaesthesiology, University of Messina
He is Director of the Unit of Clinical Neurobiology and Neuromuscular
Diseases
Scientific Team: A. Mazzeo, C. Rodolico, M. Aguennouz,
A. Toscano, M.G. De Pasquale
Research facilities: Laboratory for autonomic nervous
system investigation, muscle and nerve biopsy, immunohistochemistry
and immunoblot for onconeural
antibodies, anti-MAG, anti-gangliosides
and anti-sulfatides antibodies testing, DNA microarrays.
Areas of interest: Neuromuscular diseases.
Recent Publications:
Laurà M, Mazzeo A, Aguennouz M, Santoro M, Catania MA, Migliorato
A, Calapai G, Vita G. Immunolocalization and activation of nuclear
factor-kB in the sciatic nerves of rats with experimental autoimmune
neuritis. Journal of Neuroimmunology 2006;174:32-38.
Messina S, Bitto A, Aguennouz M, Minutoli L, Monici MC, Altavilla
D, Squadrito F, Vita G. Nuclear factor kappa-B blockade reduces skeletal
muscle degeneration and enhances muscle funcion in mdx mice.
Experimental Neurology 2006;198:234-241.
Messina S, Altavilla D, Aguennouz M, Seminara P, Minutoli L, Monici
MC, Bitto A, Mazzeo A, Marini H, Squadrito F, Vita G. Lipid peroxidation
inhibition blunts nuclear factor-kB activation, reduces skeletal
muscle degeneration, and enhances muscle funcion in mdx mice.
American Journal of Pathology 2006;168:918-926.
Conti A, Aguennouz M, La Torre D, Cardali S, Angileri FF, Buemi
C, Tomasello C, Iacopino DG, d’Avella D, Vita G, Tomasello
F. Expression of the tumor necrosis factor receptor-associated factors
1 and 2 and regulation of the nuclear factor-kB antiapoptotic activity
in human gliomas. Journal of Neurosurgery 2005;103:873-881.
La Torre D, de Divitiis O, Conti A, Angileri FF, Cardali S, Aguennouz
M, Aragona M, Panetta S, d’Avella D, Vita G, La Torre F, Tomasello
F. Expression of telomeric repeat binding factor-1 in astroglial
brain tumors. Neurosurgery 2005;56:802-810.
Rodolico C, Mazzeo A, Toscano A, Messina S, Aguennouz M, Gaeta
M, Messina C, Vita G. Specific matrix metalloproteinase expression
in focal myositis: an immunopathological study. Acta Neurologica
Scandinavica 2005;112:173-177.
Angileri F, Aguennouz M, Conti A, La Torre D, Cardali S, Crupi R, Tomasello C, Germanò A, Vita G, Tomasello F. Nuclear Factor-κB activation and differential expression of Survivin and Bcl-2 in human grade II-IV astrocytomas. Cancer 2008 (in press).
Messina S, Mazzeo A, Bitto A, Aguennouz M, Migliorato A, De Pasquale MG, Minutoli L, Altavilla D, Zentilin L, Giacca M, Squadrito F, Vita G. VEGF overexpression via adeno-associated virus gene transfer promotes skeletal muscle regeneration and enhances muscle function in mdx mice. The FASEB Journal 2007;21:3737-3746.
Di Leo R, Musumeci O, de Gregorio C, Recupero A, Grimaldi P, Messina C, Coglitore S, Vita G, Toscano A. Evidence of cardiovascular autonomic impairment in mitochondrial disorders. Journal of Neurology 2007;254:1498-1503.
